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Showing content with the highest reputation on 01/02/21 in all areas
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What's your top 3, all time favorite comfort food? Here's my list: 1. Maha Blanca (my wife's version) 2. Spaghetti (my wife's version, no other version) 3. Happy Lemon Tiger Sugar1 point
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Have You Been Vaccinated? - What Covid 19 Vaccine Did You Get (Answers can be changed anytime) Don't forget to answer the survey. Thanks!1 point
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Magic The Gathering There's always more to know, which is part of Magic's appeal. It is complex and requires great thought and effort. The game is worth it, though, and while it is fantastic to play, the best part of all are the friends you end up making.1 point
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Unforgettable Childhood Movies - Tell Your Story How You Were Able To Watch It1 point
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RULES: 1. Tell from which movie the dialogue is from. 2. Give a movie line for the next member to guess. 3. No cheating, Don't use search engines! “Wow! All of you bigger than the Action Figures”1 point
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What is your favorite milk tea flavor? What’s your flavor today?1 point
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Perfumes - All About Scents (Box and Bottle Pics) I know there are many people who collect perfumes out there, share with us your stash ?1 point
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What's Your Car Brand? Why? Please don't forget to answer the survey ?1 point
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Hi Guys, post your cute pet photos here! It would be great if you could include your pet's names and other details. Who wants to start?1 point
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Bread Crumbs * combination Chow & Spitz * born 13 Sep. 2020 * picture was taken 28 Nov. 20201 point
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As software and apps are upgraded, old hardware has a harder time keeping up. My old phone could hardly cope with the the things I needed to do. So I bought a new one that would suit me needs better1 point
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2 packs of these (in one cup) gets me going! haha. yumm! I feel like getting one now!1 point
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I will pick the brand that will be given free by the Japanese government. It will be free here to all Filipino OWFs. When the pandemic started the Japanese gave EVERYONE 100,000 Yen. Regardless if they were Japanese or Filipinos (or any nationality). The only requirement was you had to be registered with the city.1 point
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Historia de Un Amor by David Bustamante. I was singing it on karaoke this past Christmas and it stuck still this 2021. *sigh*1 point
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Well its true that the best part is meeting other players. Whether yoy are playing casually or competitive depends on what your game play is. There are high level of competition and there are just those you like yo have fun with other peoples. Depends on you style. Others prefer to play commander (edh) the feel of politics and all1 point
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AstraZeneca is a British-Swedish multinational pharmaceutical and biopharmaceutical company that focuses on the development and commercialization of prescription medicine. Their medicines are targeted for the treatment of cardiovascular, metabolic, respiratory, inflammation, autoimmune, oncology, infection, and neuroscience diseases. AstraZeneca collaborated with the University of Oxford to create a COVID-19 vaccine. How their vaccine works: Like Russia’s Sputnik V, AstraZeneca’s vaccines use a genetically altered virus called adenovirus. This virus, which is not harmful to recipients, will carry spike protein (like the “crowns” in coronavirus). Injecting this, in theory, will help the immune system to recognize and attack coronavirus. AstraZeneca’s vaccine requires a regular fridge temperature for storage. Status development: AstraZeneca and the University of Oxford announced on December 8 that it finished the Phase 3 interim analysis for the vaccine. The researchers noted that the efficacy rate for two doses – with the first dose at half strength – reached 90 percent. While a combination of two full-strength doses only resulted in 62 percent efficacy. Issues and concerns: Scientists questioned the vaccine efficacy rate after the reported error in dosage. In a report published by the New York Times on November 25, experts inquired how the combination of half dosage for the first shot and full dosage for the second shot resulted in a 90 percent efficacy rate.1 point
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COVAX Facility, also known as the COVID-19 Vaccines Global Acces Facility, is a global mechanism designed to guarantee rapid, fair, and equitable access to COVID-19 vaccines worldwide. It is co-led by Gavi, an international organization created to improve access to new and underused vaccines, along with the Coalition for Epidemic Preparedness Innovations and the World Health Organization. The Philippines joined COVAX Facility in July. How does COVAX Facility work? “The COVAX Facility will make investments across a broad portfolio of promising vaccine candidates (including those being supported by CEPI) to make sure at-risk investment in manufacturing happens now,” Gavi explained. Since it follows a pooling process, COVAX can ensure rapid access to vaccines. Status about COVID-19 vaccine: According to the Philippines’ vaccine czar Galvez, about 80 percent of the vaccines in the global market were already taken by rich countries. The COVAX Facility, on the other hand, was able to acquire 2 percent. This means that the country is “fighting” to secure the other 18 percent of the vaccine supply.1 point
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US-based multinational pharmaceutical corporation, Pfizer, is also known as one of the world’s largest pharmaceutical companies. On the other hand, BioNTech SE is a German biotechnology company that focuses on individualized immunotherapies. How their vaccine works: Pfizer-BioNTech’s vaccine is similar to Moderna’s mRNA-1273 in the sense that it uses mRNA to eliminate the new coronavirus SARS-CoV-2. Pfizer-BioNTech’s vaccine requires storage with a temperature of -70 degrees Celsius. Status development: Pfizer and BioNTech concluded the Phase 3 study for their vaccine on November 18. Meanwhile, the USFDA on December 12 granted an emergency use authorization for the vaccine, and on December 14 started its use in New York City. The United Kingdom, the first country in the world to conduct mass inoculation against COVID-19 starting December 8, likewise used the vaccine developed by Pfizer and BioNTech. On Monday, Singapore Prime Minister Lee Hsien Long announced the approval of the Pfizer-BioNTech vaccine for his country’s mass vaccination program that will likely begin by end-December. Later, Jordan announced it had approved emergency use of the Pfizer-BioNTech coronavirus vaccine. Pfizer’s vaccine showed a 95 percent efficacy rate during its study. Issues and concerns: U.K.’s Medicines and Healthcare Products Regulatory Agency (MHRA) on December 10 issued an anaphylaxis warning on the Pfizer-BioNTech vaccine after reports of three cases of adverse reactions. According to MHRA, there were two reports of anaphylaxis and one possible allergic reaction after administering the vaccines. “Any person with a history of anaphylaxis to a vaccine, medicine or food should not receive the Pfizer BioNTech vaccine,” MHRA Chief Executive June Raine said in a statement. “Most people will not get anaphylaxis and the benefits in protecting people against COVID-19 outweigh the risks… You can be completely confident that this vaccine has met the MHRA’s robust standards of safety, quality and effectiveness,” Raine assured. Roll-out: Pfizer-BioNTech began its first shipment of the vaccines to several states in America on December 13.1 point
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Sinovac is a Beijing-based biopharmaceutical company founded in 2001. Their focus is on the research, development, and manufacture of vaccines against infectious diseases such as H1N1 influenza and COVID-19. How their vaccine works: Unlike Moderna, which uses RNA in its vaccines, Sinovac’s CoronaVac relies on inactivated pathogens that are grown and killed in laboratories. Similar to the inactivated vaccines used for polio, this vaccine uses the killed viruses to produce antigens which signal the immune system to attack the virus causing COVID-19. CoronaVac can be stored in a standard refrigerator at 2-8 degrees Celsius. Status development: In October, Sinovac submitted its application to the Food and Drug Administration (FDA) of the Philippines to conduct Phase 3 clinical trials for CoronaVac in the country. COVID-19 policy chief implementer and vaccine czar Carlito Galvez, Jr. earlier said that the vaccine may be the first to be rolled out in the country, probably by the first quarter of 2021. Sinovac has yet to report the efficacy rate of CoronaVac. Issues and concerns: Sinovac has been recently reported to be involved in a bribery scandal. However, the company cleared out its CEO, Yin Weidong, of the accusations. Roll-out: According to Galvez, they are already finalizing negotiations with Sinovac. He said the pharmaceutical firm vowed to supply vaccines in the country by April 2021. However, Galvez negotiated to get it by March.1 point
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Moderna is a Massachusetts-based biotechnology company that focuses on drug discovery and development. It also makes vaccines based on mRNA. How their vaccine works: The Centers for Disease Control and Prevention (CDC) website said the vaccine, also known as “mRNA-1273,” basically uses mRNA, a genetic molecule that carries the instructions for making proteins in our body. This vaccine requires two shots that will be given 28 days apart. The mRNA in the vaccine will instruct cells to make a harmless spike protein – which can also be seen on the surface of SARS-CoV-2, the new strain of coronavirus that causes respiratory disease COVID-19, said the CDC website. According to the CDC, the protruding spikes and spike fragments in the cell will then be recognized by the immune system and cause an immune response that produces antibodies. These antibodies stop the coronavirus from attacking other cells by attaching to the virus’s spikes. The antibodies can also mark the virus so other cells can detect and destroy it. Moderna’s vaccine needs to be stored at -20C. Status development: Moderna announced last month that it has finished the first interim analysis of the Phase 3 study for mRNA-1273. According to the company, the study showed that its vaccine has an efficacy rate of 94.5 percent. Issues and concerns: Based on a study published in The New England Journal of Medicine, Moderna’s vaccine can protect for at least three months. But according to a report by the New York Times, since the vaccine is new, researchers still have no idea how long the vaccine’s protection will last. The report added that the number of antibodies and T-cells might reduce months after the vaccination. However, memory B-cells and memory-T cells might retain the information about the coronavirus even after years or decades. Roll-out: Moderna applied for emergency use authorization to the U.S. Food and Drug Administration (USFDA) on November 30. USFDA is set to decide on its application on December 17. If approved, Moderna can start releasing its vaccines in the US before the end of the month.1 point
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Black coffee please. Ready to drink. I don’t want to burn my tongue sipping coffee, again.1 point
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1. Black Scoop 2. BLK 513 3. Halo-Halo I'm usually sedated after consuming any of these.1 point