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Showing content with the highest reputation on 01/02/21 in all areas

  1. 4 points
  2. What Are You Wearing Today? Post Your Pic
    2 points
  3. Always have been, always will be... Ginebra!
    2 points
  4. tamago Posted on Sept 5 2008 What song or music are you listening to right now? Let's post!
    1 point
  5. What's your top 3, all time favorite comfort food? Here's my list: 1. Maha Blanca (my wife's version) 2. Spaghetti (my wife's version, no other version) 3. Happy Lemon Tiger Sugar
    1 point
  6. Magic The Gathering There's always more to know, which is part of Magic's appeal. It is complex and requires great thought and effort. The game is worth it, though, and while it is fantastic to play, the best part of all are the friends you end up making.
    1 point
  7. Who are you rooting for? Barangay Ginebra, Phoenix Fuel Masters, TNT Tropang Giga, San Miguel Beermen, Meralco Bolts, Alaska, Magnolia Hotshots, Rain or Shine, Nlex Road Warriors, Blackwater Elite, North Port Batang Pier, Terrafirma Dyip
    1 point
  8. RULES: 1. Tell from which movie the dialogue is from. 2. Give a movie line for the next member to guess. 3. No cheating, Don't use search engines! “Wow! All of you bigger than the Action Figures”
    1 point
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  10. Perfumes - All About Scents (Box and Bottle Pics) I know there are many people who collect perfumes out there, share with us your stash ?
    1 point
  11. Why Did You Buy a New Cellphone? Please don't forget to answer the survey ?
    1 point
  12. What's Your Car Brand? Why? Please don't forget to answer the survey ?
    1 point
  13. Hi Guys, post your cute pet photos here! It would be great if you could include your pet's names and other details. Who wants to start?
    1 point
  14. The State of Philippine Cinema and TV
    1 point
  15. He he he ... If I'm not mistaken, no vaccines have been authorized for use in the Philippines as of this writing. Sat. 02 Jan. If anyone answers "yes" now, he / she may be investigated by the government in reference to unauthorized use of vaccines.
    1 point
  16. As software and apps are upgraded, old hardware has a harder time keeping up. My old phone could hardly cope with the the things I needed to do. So I bought a new one that would suit me needs better
    1 point
  17. Ayokong uminom nito. Mighty Tea kasi eh.?
    1 point
  18. I saw the original Pet Sematary (1989) on VHS when I was 7 years old. At the time, it was the scariest thing I've ever watched and the novel on which it was based upon is (still) the creepiest thing I ever read. I watched the entire film from start to finish without pausing (and I was alone, bec my mother didn't allow me to watch scary shit like that) but it got under my skin so much that I never looked at our pet cat the same way ever again. Now, more than two decades later, it's still one of those movies that scares the bejesus out of me. Oh how I miss the good times.
    1 point
  19. Harry Styles - Adore You Walk in your rainbow paradise (paradise) Strawberry lipstick state of mind (state of mind) I get so lost inside your eyes Would you believe it? You don't have to say you love me You don't have to say nothing You don't have to say you're mine Honey I'd walk through fire for you Just let me adore you Oh, honey I'd walk through fire for you Just let me adore you Like it's the only thing I'll ever do Like it's the only thing I'll ever do Your wonder under summer skies (summer skies) Brown skin and lemon over ice Would you believe it? You don't have to say you love me I just wanna tell you something Lately you've been on my mind Honey I'd walk through fire for you Just let me adore you Oh, honey I'd walk through fire for you Just let me adore you Like it's the only thing I'll ever do Like it's the only thing I'll ever do I'd walk through fire for you Just let me adore you Oh, honey I'd walk through fire for you Just let me adore you Like it's the only thing I'll ever do I'd walk through fire for you Just let me adore you Oh, honey Oh, honey I'd walk through fire for you Just let me adore you Oh, honey Just let me adore you Like it's the only thing I'll ever do
    1 point
  20. Dua Lipa - Don't Start Now If you don't wanna see me Did a full 180, crazy Thinking 'bout the way I was Did the heartbreak change me? Maybe But look at where I ended up I'm all good already So moved on, it's scary I'm not where you left me at all, so If you don't wanna see me dancing with somebody If you wanna believe that anything could stop me Don't show up, don't come out Don't start caring about me now Walk away, you know how Don't start caring about me now Aren't you the guy who tried to Hurt me with the word "goodbye"? Though it took some time to survive you I'm better on the other side I'm all good already So moved on, it's scary I'm not where you left me at all, so If you don't wanna see me dancing with somebody If you wanna believe that anything could stop me Don't show up, don't come out Don't start caring about me now Walk away, you know how Don't start caring about me now ('bout me now, 'bout me) Oh, oh Don't come out, out, out Don't show up, up, up Don't start now (oh) Oh, oh Don't come out, out I'm not where you left me at all, so If you don't wanna see me dancing with somebody If you wanna believe that anything could stop me Don't show up (don't show up), don't come out (don't come out) Don't start caring about me now ('bout me now) Walk away (walk away), you know how (you know how) Don't start caring about me now (so) Oh, oh Don't come out, out, out Don't show up, up, up Walk away, walk away (so) Oh, oh Don't come out, out, out Don't show up, up, up Walk away, walk away, oh
    1 point
  21. 2 packs of these (in one cup) gets me going! haha. yumm! I feel like getting one now!
    1 point
  22. 1 point
  23. Toyota Innova 2.8 E Black The family journey
    1 point
  24. New gadgets provide a much better technology, a much improve storage capacity, a much clearer image, better video quality and overall performance. We always hope that having a better gadget will somehow improves our life and overall prestige.
    1 point
  25. Novavax, a late-stage US biotechnology company, focuses on the discovery, development, and commercialization of vaccines to prevent serious infectious diseases. This Maryland company is smaller compared to other vaccine manufacturers. They received a $1.6 billion grant from the US government’s Operation Warp Speed to produce 100 million doses by 2021. How their vaccines work: According to an article published in the Science Magazine, a peer-reviewed academic journal of the American Association for the Advancement of Science, Novavax first inserts baculovirus into moth cells. The baculovirus, a pathogen that attacks insects, will make moth cells produce a protein called spike – which is present in coronavirus. The spikes are then harvested by scientists and mixed with a “synthetic soap like particle” where the spikes can latch on. A compound called saponin, also derived from plants and trees, is also added to boost the immune response. The NVX‑CoV2373 vaccine aims to produce anti spike antibodies that can block SARS-CoV-2 infection. Status development: As of November 30, Novavax said in a statement that it has completed the enrollment of its 15,000-patient UK Phase 3 trial. The company added that has fully enrolled the Phase 2b trial in South Africa. “Novavax expects its pivotal Phase 3 clinical trial in the United States and Mexico to begin in the coming weeks. More than 100 trial sites have been selected with some alternate sites in place, should they be needed,” the company added. Roll-out: Since the vaccine is still in its early trial stages, there is still no expected release date.
    1 point
  26. AstraZeneca is a British-Swedish multinational pharmaceutical and biopharmaceutical company that focuses on the development and commercialization of prescription medicine. Their medicines are targeted for the treatment of cardiovascular, metabolic, respiratory, inflammation, autoimmune, oncology, infection, and neuroscience diseases. AstraZeneca collaborated with the University of Oxford to create a COVID-19 vaccine. How their vaccine works: Like Russia’s Sputnik V, AstraZeneca’s vaccines use a genetically altered virus called adenovirus. This virus, which is not harmful to recipients, will carry spike protein (like the “crowns” in coronavirus). Injecting this, in theory, will help the immune system to recognize and attack coronavirus. AstraZeneca’s vaccine requires a regular fridge temperature for storage. Status development: AstraZeneca and the University of Oxford announced on December 8 that it finished the Phase 3 interim analysis for the vaccine. The researchers noted that the efficacy rate for two doses – with the first dose at half strength – reached 90 percent. While a combination of two full-strength doses only resulted in 62 percent efficacy. Issues and concerns: Scientists questioned the vaccine efficacy rate after the reported error in dosage. In a report published by the New York Times on November 25, experts inquired how the combination of half dosage for the first shot and full dosage for the second shot resulted in a 90 percent efficacy rate.
    1 point
  27. The Gamelaya Research Institute of Epidemiology and Microbiology is a Russian medical-research institute founded in 1891. According to Gamelaya, it “runs one of the unique “virus libraries” in the world and has its own vaccine production facility.” Aside from their research for the COVID-19 vaccine, they are also working to develop a vaccine against Ebola and the Middle East Respiratory Syndrome (MERS). How their vaccine works: Sputnik V is a two-part adenovirus-based vector vaccine. It uses a vector (an engineered virus that lacks the gene to reproduce) to send a message in cells to produce spike proteins. “The gene from adenovirus, which causes the infection, is removed while a gene with the code of a protein from another virus spike is inserted,” the institute explained. “This inserted element is safe for the body but still helps the immune system to react and produce antibodies, which protect us from the infection,” it added. Sputnik V is stored in a regular refrigerator temperature (in dry form). Status development: Gamaleya on November 24 announced that it has finished the second interim analysis of clinical trial data for Sputnik V. “The Sputnik V vaccine’s efficacy is confirmed at 91.4% based on data analysis of the final control point of clinical trials. The Sputnik V vaccine efficacy against severe cases of coronavirus is 100%,” Gamaleya reported. In October, the Russian Direct Investment Fund (RDIF) submitted applications to the World Health Organization for an Emergency Use Listing and prequalification of Sputnik V. According to a report on Monday, Russia is almost done completing its clinical trials for its COVID-19 vaccine for domestic animals and mink. Issues and concerns: Some scientists have recently expressed concerns towards Sputnik V due to a “lack of safety data.” However, Russia denounced the criticisms.
    1 point
  28. US-based multinational pharmaceutical corporation, Pfizer, is also known as one of the world’s largest pharmaceutical companies. On the other hand, BioNTech SE is a German biotechnology company that focuses on individualized immunotherapies. How their vaccine works: Pfizer-BioNTech’s vaccine is similar to Moderna’s mRNA-1273 in the sense that it uses mRNA to eliminate the new coronavirus SARS-CoV-2. Pfizer-BioNTech’s vaccine requires storage with a temperature of -70 degrees Celsius. Status development: Pfizer and BioNTech concluded the Phase 3 study for their vaccine on November 18. Meanwhile, the USFDA on December 12 granted an emergency use authorization for the vaccine, and on December 14 started its use in New York City. The United Kingdom, the first country in the world to conduct mass inoculation against COVID-19 starting December 8, likewise used the vaccine developed by Pfizer and BioNTech. On Monday, Singapore Prime Minister Lee Hsien Long announced the approval of the Pfizer-BioNTech vaccine for his country’s mass vaccination program that will likely begin by end-December. Later, Jordan announced it had approved emergency use of the Pfizer-BioNTech coronavirus vaccine. Pfizer’s vaccine showed a 95 percent efficacy rate during its study. Issues and concerns: U.K.’s Medicines and Healthcare Products Regulatory Agency (MHRA) on December 10 issued an anaphylaxis warning on the Pfizer-BioNTech vaccine after reports of three cases of adverse reactions. According to MHRA, there were two reports of anaphylaxis and one possible allergic reaction after administering the vaccines. “Any person with a history of anaphylaxis to a vaccine, medicine or food should not receive the Pfizer BioNTech vaccine,” MHRA Chief Executive June Raine said in a statement. “Most people will not get anaphylaxis and the benefits in protecting people against COVID-19 outweigh the risks… You can be completely confident that this vaccine has met the MHRA’s robust standards of safety, quality and effectiveness,” Raine assured. Roll-out: Pfizer-BioNTech began its first shipment of the vaccines to several states in America on December 13.
    1 point
  29. Moderna is a Massachusetts-based biotechnology company that focuses on drug discovery and development. It also makes vaccines based on mRNA. How their vaccine works: The Centers for Disease Control and Prevention (CDC) website said the vaccine, also known as “mRNA-1273,” basically uses mRNA, a genetic molecule that carries the instructions for making proteins in our body. This vaccine requires two shots that will be given 28 days apart. The mRNA in the vaccine will instruct cells to make a harmless spike protein – which can also be seen on the surface of SARS-CoV-2, the new strain of coronavirus that causes respiratory disease COVID-19, said the CDC website. According to the CDC, the protruding spikes and spike fragments in the cell will then be recognized by the immune system and cause an immune response that produces antibodies. These antibodies stop the coronavirus from attacking other cells by attaching to the virus’s spikes. The antibodies can also mark the virus so other cells can detect and destroy it. Moderna’s vaccine needs to be stored at -20C. Status development: Moderna announced last month that it has finished the first interim analysis of the Phase 3 study for mRNA-1273. According to the company, the study showed that its vaccine has an efficacy rate of 94.5 percent. Issues and concerns: Based on a study published in The New England Journal of Medicine, Moderna’s vaccine can protect for at least three months. But according to a report by the New York Times, since the vaccine is new, researchers still have no idea how long the vaccine’s protection will last. The report added that the number of antibodies and T-cells might reduce months after the vaccination. However, memory B-cells and memory-T cells might retain the information about the coronavirus even after years or decades. Roll-out: Moderna applied for emergency use authorization to the U.S. Food and Drug Administration (USFDA) on November 30. USFDA is set to decide on its application on December 17. If approved, Moderna can start releasing its vaccines in the US before the end of the month.
    1 point
  30. Mom! Are you sure this water's sanitary? It looks questionable to me!
    1 point
  31. It's not flying, it's falling in style
    1 point
  32. Does the ice water really work?
    1 point
  33. 1. Black Scoop 2. BLK 513 3. Halo-Halo I'm usually sedated after consuming any of these.
    1 point
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