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Showing content with the highest reputation on 01/01/21 in all areas
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I'm blackbelt in Taekwondo, I train every Friday, Saturday and Sunday for 2 hours. I also play basketball on weekends. What sport do you play?2 points
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Just wondering who else is into Martial Arts? What level are you in? Have you competed?2 points
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want to go back to running kaso need ko pa magpababa ng weight. injured both knees kaya nde na ata pde sa long distance2 points
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It will be meat depot for me. You can have a premium tasting steak in a fraction of its price if eaten elsewhere.2 points
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New gadgets provide a much better technology, a much improve storage capacity, a much clearer image, better video quality and overall performance. We always hope that having a better gadget will somehow improves our life and overall prestige.2 points
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I used to play soccer back in high school. And then I trained for MMA for two months, and then I started watching YouTube MMA channels. I also play table tennis and I swim every summer.2 points
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MMA training for 2 months, and then proceeded to watch YouTube MMA channels for 2 years counting. I’m now a YouTube MMA certified subscriber ?2 points
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What's your favorite burger, fried chicken, fries, and fast food chain in the Philippines?1 point
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I used to play Mobile Legends bangbang, when LOL announced that they developed LOL on Mobile I was so excited to try it. Now I'm better at gameplay, love the graphics and there's less toxic players atm. ? My favorite champion is LUX the mage.1 point
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Why do they wan to live their retirement lives in the Philippines? There are those not of retirement age who already want to live in their provinces back in the Phils. Are these the first generation immigrants?1 point
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Originally Posted by dolphin722 on 16 November 2004 - 05:06 PM What kind of foods touches the "senti" in you? Like, macaroni soup with evaporated milk - brings back my childhood memories of my mom serving this to me whenever i am sick, or Master Spanish Sardines - istudyante pa lang ako noon, at isang lata nito, napapakain kaming 8 magbabarkada ... dinadaan na lang sa kanin. Simot talaga ito pati mantika, hehehe! Sarsi with egg. paborito ng tatay at kuya ko. If I want them to smile, bigyan ko lang sila nito.1 point
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Arellano University Chiefs Colegio de San Juan de Letran Knights College of Saint Benilde Blazers Emilio Aguinaldo College Generals Jose Rizal University Heavy Bombers Lyceum of the Philippines University Pirates Mapua Institute of Technology Cardinals San Beda University Red Lions San Sebastian College - Recoletos Stags University of Perpetual Help Dalta Systems Altas1 point
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Chess Grand Master Wesley So Wesley Barbasa So (born October 9, 1993) is a Filipino-American chess grandmaster and current World Fischer Random Chess Champion. He is a three-time Filipino Chess Champion and a two-time U.S. Chess Champion, in 2017 and 2020. On the March 2017 FIDE rating list, he was ranked number two in the world and had an Elo rating of 2822, making him the fifth-highest rated player in history. A former chess prodigy, So became the youngest player to pass a 2600 Elo rating in October 2008, breaking the record previously held by Magnus Carlsen. This record has since been broken by John M. Burke. In early 2013, So passed 2700 and in January 2017 he became the 11th player to pass 2800 Elo. So represented the Philippines until transferring to the United States in 2014. He won the 2015 Bilbao Chess Masters, the 2016 Grand Chess Tour title after claiming victory in the Sinquefield Cup and London Chess Classic, and the 2017 Tata Steel Masters. He represented the US on board 3 at the 42nd Chess Olympiad, winning team and individual gold. On 2 November 2019, So became the first official Fischer Random world champion after defeating Carlsen 13½–2½ to win the FIDE World Fischer Random Chess Championship.1 point
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Novavax, a late-stage US biotechnology company, focuses on the discovery, development, and commercialization of vaccines to prevent serious infectious diseases. This Maryland company is smaller compared to other vaccine manufacturers. They received a $1.6 billion grant from the US government’s Operation Warp Speed to produce 100 million doses by 2021. How their vaccines work: According to an article published in the Science Magazine, a peer-reviewed academic journal of the American Association for the Advancement of Science, Novavax first inserts baculovirus into moth cells. The baculovirus, a pathogen that attacks insects, will make moth cells produce a protein called spike – which is present in coronavirus. The spikes are then harvested by scientists and mixed with a “synthetic soap like particle” where the spikes can latch on. A compound called saponin, also derived from plants and trees, is also added to boost the immune response. The NVX‑CoV2373 vaccine aims to produce anti spike antibodies that can block SARS-CoV-2 infection. Status development: As of November 30, Novavax said in a statement that it has completed the enrollment of its 15,000-patient UK Phase 3 trial. The company added that has fully enrolled the Phase 2b trial in South Africa. “Novavax expects its pivotal Phase 3 clinical trial in the United States and Mexico to begin in the coming weeks. More than 100 trial sites have been selected with some alternate sites in place, should they be needed,” the company added. Roll-out: Since the vaccine is still in its early trial stages, there is still no expected release date.1 point
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AstraZeneca is a British-Swedish multinational pharmaceutical and biopharmaceutical company that focuses on the development and commercialization of prescription medicine. Their medicines are targeted for the treatment of cardiovascular, metabolic, respiratory, inflammation, autoimmune, oncology, infection, and neuroscience diseases. AstraZeneca collaborated with the University of Oxford to create a COVID-19 vaccine. How their vaccine works: Like Russia’s Sputnik V, AstraZeneca’s vaccines use a genetically altered virus called adenovirus. This virus, which is not harmful to recipients, will carry spike protein (like the “crowns” in coronavirus). Injecting this, in theory, will help the immune system to recognize and attack coronavirus. AstraZeneca’s vaccine requires a regular fridge temperature for storage. Status development: AstraZeneca and the University of Oxford announced on December 8 that it finished the Phase 3 interim analysis for the vaccine. The researchers noted that the efficacy rate for two doses – with the first dose at half strength – reached 90 percent. While a combination of two full-strength doses only resulted in 62 percent efficacy. Issues and concerns: Scientists questioned the vaccine efficacy rate after the reported error in dosage. In a report published by the New York Times on November 25, experts inquired how the combination of half dosage for the first shot and full dosage for the second shot resulted in a 90 percent efficacy rate.1 point
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US-based multinational pharmaceutical corporation, Pfizer, is also known as one of the world’s largest pharmaceutical companies. On the other hand, BioNTech SE is a German biotechnology company that focuses on individualized immunotherapies. How their vaccine works: Pfizer-BioNTech’s vaccine is similar to Moderna’s mRNA-1273 in the sense that it uses mRNA to eliminate the new coronavirus SARS-CoV-2. Pfizer-BioNTech’s vaccine requires storage with a temperature of -70 degrees Celsius. Status development: Pfizer and BioNTech concluded the Phase 3 study for their vaccine on November 18. Meanwhile, the USFDA on December 12 granted an emergency use authorization for the vaccine, and on December 14 started its use in New York City. The United Kingdom, the first country in the world to conduct mass inoculation against COVID-19 starting December 8, likewise used the vaccine developed by Pfizer and BioNTech. On Monday, Singapore Prime Minister Lee Hsien Long announced the approval of the Pfizer-BioNTech vaccine for his country’s mass vaccination program that will likely begin by end-December. Later, Jordan announced it had approved emergency use of the Pfizer-BioNTech coronavirus vaccine. Pfizer’s vaccine showed a 95 percent efficacy rate during its study. Issues and concerns: U.K.’s Medicines and Healthcare Products Regulatory Agency (MHRA) on December 10 issued an anaphylaxis warning on the Pfizer-BioNTech vaccine after reports of three cases of adverse reactions. According to MHRA, there were two reports of anaphylaxis and one possible allergic reaction after administering the vaccines. “Any person with a history of anaphylaxis to a vaccine, medicine or food should not receive the Pfizer BioNTech vaccine,” MHRA Chief Executive June Raine said in a statement. “Most people will not get anaphylaxis and the benefits in protecting people against COVID-19 outweigh the risks… You can be completely confident that this vaccine has met the MHRA’s robust standards of safety, quality and effectiveness,” Raine assured. Roll-out: Pfizer-BioNTech began its first shipment of the vaccines to several states in America on December 13.1 point
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Moderna is a Massachusetts-based biotechnology company that focuses on drug discovery and development. It also makes vaccines based on mRNA. How their vaccine works: The Centers for Disease Control and Prevention (CDC) website said the vaccine, also known as “mRNA-1273,” basically uses mRNA, a genetic molecule that carries the instructions for making proteins in our body. This vaccine requires two shots that will be given 28 days apart. The mRNA in the vaccine will instruct cells to make a harmless spike protein – which can also be seen on the surface of SARS-CoV-2, the new strain of coronavirus that causes respiratory disease COVID-19, said the CDC website. According to the CDC, the protruding spikes and spike fragments in the cell will then be recognized by the immune system and cause an immune response that produces antibodies. These antibodies stop the coronavirus from attacking other cells by attaching to the virus’s spikes. The antibodies can also mark the virus so other cells can detect and destroy it. Moderna’s vaccine needs to be stored at -20C. Status development: Moderna announced last month that it has finished the first interim analysis of the Phase 3 study for mRNA-1273. According to the company, the study showed that its vaccine has an efficacy rate of 94.5 percent. Issues and concerns: Based on a study published in The New England Journal of Medicine, Moderna’s vaccine can protect for at least three months. But according to a report by the New York Times, since the vaccine is new, researchers still have no idea how long the vaccine’s protection will last. The report added that the number of antibodies and T-cells might reduce months after the vaccination. However, memory B-cells and memory-T cells might retain the information about the coronavirus even after years or decades. Roll-out: Moderna applied for emergency use authorization to the U.S. Food and Drug Administration (USFDA) on November 30. USFDA is set to decide on its application on December 17. If approved, Moderna can start releasing its vaccines in the US before the end of the month.1 point
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Red Bull This is my quick food. I don't need anything else. Just a can of this will get me going for 6 hours. Now if you're old like me you will feel a slight palpitation so watch it. Don't over do it, maybe try half a can first. ?1 point
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It saddens me that it will be a few years more before I can taste this Ice Cream. So creamy, milky, no extenders.1 point
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Conflicting points of view. I drink the cheap during regular days, and the expensive ones during memorable occasions.1 point
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